In Vitro Fertilisation

(asked on 10th March 2020) - View Source

Question to the Department of Health and Social Care:

To ask Her Majesty's Government, further to the Written Answer by Lord Bethell on 5 March (HL1700), what were the mitochondrial DNA mutations in each of the 17 applications considered by the Human Fertilisation and Embryology Authority that have now been approved; and on what dates each application was (1) made, and (2) approved.


Answered by
Lord Bethell Portrait
Lord Bethell
This question was answered on 23rd March 2020

The following table shows the gene affected and the mutation in each application, the dates each application was made and approved by the Human Fertilisation and Embryology Authority (HFEA) Statutory Approvals Committee.

HFEA Application reference

Gene affected by mutation

Mutation

Date received

Date approved by the HFEA Statutory Approvals Committee

M0001

MT-TK

Details omitted to protect patient identity

28 June 2017

31 August 2017

M0002

MT-TK

Details omitted to protect patient identity

4 September 2017

26 October 2017

M0007

MT-ND1

m.3460 G>A

13 March 2018

24 May 2018

M0003

MT-TL1

Details omitted to protect patient identity

25 September 2017

26 July 2018

M0005

MT-TL1

m.3243 A>G

5 December 2017

26 July 2018

M0008

MT-TL1

m.3243 A>G

15 March 2018

26 July 2018

M0004

MT-TK

Details omitted to protect patient identity

4 December 2017

30 August 2018

M0006

MT-TS1

Details omitted to protect patient identity

9 January 2018

30 August 2018

M0009

MT-TI

m.4300 A>G

28 June 2018

27 September 2018

M0010

MT-TI

m.4300 A>G

11 July 2018

27 September 2018

M0013

MT-ND4

m.11778 G>A

14 July 2018

25 October 2018

M0012

MT-ND1

m.3460 G>A

13 July 2018

25 October 2018

M0014

MT-ND4

m.11778 G>A

23 November 2018

31 January 2019

M0015

MT-ND4

m.11778 G>A

23 November 2018

31 January 2019

M0011

MT-ND4

m.11778 G>A

12 July 2018

29 August 2019

M0016

MT-TK

m.8344 A>G

5 July 2019

26 September 2019

M0017

MT-ND4

m.11778 G>A

22 August 2019

31 October 2019

Source:

HFEA

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