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Non-Departmental Publication (Guidance and Regulation)
Medicines and Healthcare products Regulatory Agency

Apr. 04 2024

Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines
Document: E10 – Choice of Control Group and Related Issues in Clinical Trials (PDF)

Found: thrombolytics in patients with acute myocardial infarction can reduce mortality but increase hemorrhagic stroke

Non-Departmental Publication (Guidance and Regulation)
Medicines and Healthcare products Regulatory Agency

Apr. 04 2024

Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines
Document: E2C(R2) – Periodic Benefit-Risk Evaluation Report (PDF)

Found: for evaluation & summary of key data Method of signal evaluation Action(s) taken or planned Stroke

Non-Departmental Publication (Guidance and Regulation)
Medicines and Healthcare products Regulatory Agency

Apr. 04 2024

Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines
Document: E3 – Structure and Content of Clinical Study Reports (PDF)

Found: of acute myocardial infarction, designation of the location of the infarction, characterisation of a stroke

Non-Departmental Publication (Guidance and Regulation)
Medicines and Healthcare products Regulatory Agency

Apr. 04 2024

Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines
Document: M4S(R2) – CTD on Safety (PDF)

Found: No effects on cardiac output, stroke volume, or total peripheral resistance.

Non-Departmental Publication (Guidance and Regulation)
Medicines and Healthcare products Regulatory Agency

Apr. 04 2024

Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines
Document: S7B – The Non-Clinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals (PDF)

Found: through L-type Ca2+ channels and outward repolarizing K+ currents; • phase 3: The sustained downward stroke

Non-Departmental Publication (Guidance and Regulation)
Ofqual

Apr. 03 2024

Source Page: VTQ information hub 2023 to 2024: key dates and deadlines
Document: (webpage)

Found: release for final result to centres 12-Aug-24 12-Aug-24 N/A NCFE NCFE CACHE Level 3 Certificate in Stroke

Non-Departmental Publication (Guidance and Regulation)
Ofqual

Apr. 03 2024

Source Page: VTQ information hub 2023 to 2024: key dates and deadlines
Document: (webpage)

Found: release for final result to centres 12-Aug-24 12-Aug-24 N/A NCFE NCFE CACHE Level 3 Certificate in Stroke

Non-Departmental Publication (Guidance and Regulation)
Maritime and Coastguard Agency

Mar. 28 2024

Source Page: Code of safe working practices for merchant seafarers (COSWP) 2024
Document: COSWP 2024 Edition (PDF)

Found: and hot environments 3.7.1 High humidity and high temperatures can lead to heat exhaustion and heat stroke

Departmental Publication (Guidance and Regulation)
Department of Health and Social Care

Mar. 28 2024

Source Page: General Medical Services Statement of Financial Entitlements Directions: previous directions
Document: The General Medical Services Statement of Financial Entitlements (Amendment) (No.2) Directions 2022 (PDF)

Found: The percentage of patients with atrial fibrillation in whom stroke risk has been assessed using the

Departmental Publication (Guidance and Regulation)
Department of Health and Social Care

Mar. 28 2024

Source Page: General Medical Services Statement of Financial Entitlements Directions: previous directions
Document: The General Medical Services Statement of Financial Entitlements (Amendment) Directions 2022 (PDF)

Found: Heart Failure (HF) 28 13 41 Hypertension (HYP) 6 19 25 Peripheral Arterial Disease (PAD) 2 0 2 Stroke