Mentions:
1: Christian Wakeford (Lab - Bury South) that thinking of the further after-effects of one of the biggest scandals in the health service since thalidomide - Speech Link
2: Christopher Chope (Con - Christchurch) The battle is in many ways a repetition of the thalidomide debate…The result is decaying confidence in - Speech Link
3: Christopher Chope (Con - Christchurch) I have seen other healthcare scandals in this country rightly receive recognition and redress, from thalidomide - Speech Link
Mentions:
1: Andrew Bridgen (Ind - North West Leicestershire) “Safe and effective” was the sale slogan of thalidomide. - Speech Link
Apr. 04 2024
Source Page: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use GuidelinesFound: ICH S5(R3) Guideline 102 Thalidomide CAS No.: 50-35-1 Rat NOAEL Dose Cmax AUC Rat
Oral Evidence Mar. 19 2024
Inquiry: Proposals for backbench debatesFound: In fact, it is not even possible to prove a causal link because, as with thalidomide, you would have
Asked by: Dan Carden (Labour - Liverpool, Walton)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, whether she plans to take steps to implement recommendations in the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.
Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)
We remain hugely sympathetic to the families who believe that they have suffered because of using Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group (EWG) conducted a comprehensive review of the available scientific evidence and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs and a possible causal association with adverse pregnancy outcomes.
On the recently published recommendations of the HPT All-Party Parliamentary Group, we have no plans to set up an independent review to examine the findings of the EWG. In the interests of transparency, all evidence collected and papers considered by the EWG were published in 2018, along with full minutes of its discussions. Details of conflicts of interests and how these were managed were also published. The Government is reviewing Professor Danielsson’s publication to consider if it presents any new evidence or analyses not already considered by the EWG on HPTs, and will be seeking independent expert advice from the Commission on Human Medicines in due course.
Asked by: Jeff Smith (Labour - Manchester, Withington)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, whether she has made an assessment of the potential implications for her Department’s policies of the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.
Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)
We remain hugely sympathetic to the families who believe that they have suffered due to the use of Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group conducted a comprehensive review of the available scientific evidence, and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs, and a possible causal association with adverse pregnancy outcomes.
Asked by: Jeff Smith (Labour - Manchester, Withington)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, if she will implement the recommendations in the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.
Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)
We remain hugely sympathetic to the families who believe that they have suffered due to the use of Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group conducted a comprehensive review of the available scientific evidence, and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs, and a possible causal association with adverse pregnancy outcomes.
Written Evidence Mar. 05 2024
Inquiry: Prevention in health and social careFound: Alcohol is a teratogen, like thalidomide, and the fetus cannot defend itself. 12.According to SIGN
Found: Thalidomide promotes degradation of SALL4, a transcription factor implic ated in Duane Radial Ray
Mentions:
1: Andrew Bridgen (Ind - North West Leicestershire) For posterity, we must remember that it was 11 years after the thalidomide scandal was exposed in 1961 - Speech Link
2: Andrew Bridgen (Ind - North West Leicestershire) we will see much the same, following the roll-out of the covid-19 vaccines, as we saw with Vioxx and thalidomide - Speech Link