Asked by: Ruth Jones (Labour - Newport West and Islwyn)
Question to the Home Office:
To ask the Secretary of State for the Home Department, what estimate she has made of the number of animals involved in LD50 tests by type of animal; and what assessment she has made of the effectiveness of those tests.
Answered by Dan Jarvis - Minister of State (Cabinet Office)
The Home Office publishes detailed annual statistics on the use of animals in science, including procedures for acute and sub-toxicity testing methods such as LD50 (Lethal Dose 50) and LC50 (Lethal Concentration 50). According to the latest published figures for 2024, there were 11,992 procedures in this category, and the statistics include a breakdown by species.
All testing using protected animals, including the LD50 and LC50 tests, are subject to strict regulation under the Animals (Scientific Procedures) Act 1986.
These particular tests are internationally recognised methods for assessing toxicity and are required under guidelines set by the Organisation for Economic Co-operation and Development (OECD) and the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations overseen by the Department for Environment, Food & Rural Affairs. Some authorised medicines in the UK necessitate quality control tests which require the use of animals, conducted to ensure the quality, safety, and efficacy of specific medicines. The Government is committed to non-animal alternatives in science and has published a strategy to support their development, validation and adoption. The strategy is available at:
Asked by: Ruth Jones (Labour - Newport West and Islwyn)
Question to the Department for Science, Innovation & Technology:
To ask the Secretary of State for Science, Innovation and Technology, what steps she is taking to accelerate the phasing out of the use of the LD50 test; and if she will set out a timetable for that phasing out.
Answered by Kanishka Narayan - Parliamentary Under Secretary of State (Department for Science, Innovation and Technology)
The strategy uses ‘baskets’ to group animal tests according to their readiness for replacement, based on maturity of potential alternative methods. These initial baskets will be refined in consultation with stakeholders, noting that two LD/LC50 tests are already in baskets 1 and 2 (botulinum potency and fish acute toxicity tests respectively) so are among the first targeted for phase-out. The Acutox test is a non-regulatory test and not yet validated for use in safety assessments. We will establish a new UK Centre for the Validation of Alternative Methods (UKCVAM) to accelerate alternative method validation and uptake for regulatory decision making.
Asked by: Ruth Jones (Labour - Newport West and Islwyn)
Question to the Department for Science, Innovation & Technology:
To ask the Secretary of State for Science, Innovation and Technology, what assessment she has made of the potential merits of animal-free tests such as the AcutoX for phasing out the LD50 test.
Answered by Kanishka Narayan - Parliamentary Under Secretary of State (Department for Science, Innovation and Technology)
The strategy uses ‘baskets’ to group animal tests according to their readiness for replacement, based on maturity of potential alternative methods. These initial baskets will be refined in consultation with stakeholders, noting that two LD/LC50 tests are already in baskets 1 and 2 (botulinum potency and fish acute toxicity tests respectively) so are among the first targeted for phase-out. The Acutox test is a non-regulatory test and not yet validated for use in safety assessments. We will establish a new UK Centre for the Validation of Alternative Methods (UKCVAM) to accelerate alternative method validation and uptake for regulatory decision making.
Asked by: Ruth Jones (Labour - Newport West and Islwyn)
Question to the Department for Environment, Food and Rural Affairs:
To ask the Secretary of State for Environment, Food and Rural Affairs, what steps she is taking to protect the welfare of live decapod crustaceans while held in commercial premises prior to sale.
Answered by Angela Eagle - Minister of State (Department for Environment, Food and Rural Affairs)
The Government is committed to an evidence-based and proportionate approach to setting welfare standards for decapod crustaceans. Defra has commissioned research to address a knowledge gap about how live decapods move from sea to plate. This is due to finish in 2026. In addition, a project on the welfare of decapod crustaceans across the supply chain is included in the Animal Welfare Committee’s current work plan.
Asked by: Ruth Jones (Labour - Newport West and Islwyn)
Question to the Department for Environment, Food and Rural Affairs:
To ask the Secretary of State for Environment, Food and Rural Affairs, if she will consult on legislative steps to strengthen provisions in the Hunting Act 2004.
Answered by Angela Eagle - Minister of State (Department for Environment, Food and Rural Affairs)
The Government recognises that concerns persist around illegal hunting being carried out under the guise of trail hunting; that is why we have already committed in our manifesto to put an end to trail hunting. The Government will launch a consultation in the new year on how to develop proposals for an effective ban on trail hunting.