Tackling Infectious Diseases

Carol Monaghan Excerpts

Thursday 20th April 2017 Commons Chamber

[Carol Monaghan (Glasgow North West) (SNP)]

I congratulate the hon. Member for Ealing, Southall (Mr Sharma) on securing this debate. He mentioned the three big killers worldwide—HIV, TB and malaria—and I will talk a little about them, too. The hon. Member for Stafford (Jeremy Lefroy) introduced the work on Ebola and Zika. He spoke about the possibility of a new worldwide killer disease, which could have devastating consequences, and how we might react to it. The increased UK Government funding to tackle neglected tropical diseases was mentioned by the hon. Member for Aldridge-Brownhills (Wendy Morton). Although that funding is very welcome, it is probably a drop in the ocean, given what is required to tackle these diseases properly. The hon. Member for Salisbury (John Glen) mentioned the Ebola outbreak, the difficulties in developing vaccines and treatments when there is no economic incentive to do so, and the lack of manufacturing facilities in the UK for such a huge programme.

Vaccination, antimicrobial drugs and improved hygiene mean that infectious diseases are not the massive killer they once were in the UK, but they are still a major health and economic burden for us. In other parts of the world, they are a major killer. We know that HIV and other forms of sexually transmitted infection are rampant just now in sub-Saharan Africa, but even in the UK 100,000 people are living with HIV. The number of cases of genital warts has decreased as a result of the increased use of the human papillomavirus vaccine, but rates of syphilis and gonorrhoea have significantly increased, with many cases being diagnosed late. Those conditions will have huge health implications, even here in the UK.

I wish to discuss the three diseases that the hon. Member for Ealing, Southall, talked about. Malaria is currently threatening half the world’s population, and it claims the life of a child in Africa every minute, so 50 children will have died as a result of Malaria in Africa while this debate has been going on. That is a damning statistic. Tuberculosis has killed more than any other disease in history, and last year it killed 1.8 million people globally—5,000 people every day. TB—the world’s leading killer—is airborne, which makes things difficult as it means it is hugely infectious. It is also increasingly resistant to drugs. TB does not just affect the developing world; we are seeing recurrences of it in major world cities, including London. As the hon. Gentleman mentioned, our response to TB is chronically underfunded, but as he also said, for every $1 invested in TB care, we have a yield of $30, which means there should be an incentive—a moral and economic case—for increasing our efforts.

Alexander Fleming warned in 1945 that micro-organisms could develop resistance to his new antibiotics, and unfortunately that prediction has proven correct. A report published by the World Health Organisation in 2014 said that antibiotic resistance was now a global threat, on a par with other global threats. The inappropriate prescription of antibiotics affects our ability to tackle diseases. I found some statistics about Scotland, and the picture there reflects that in the rest of the UK. In 2014, 55,000—1% of our population—were taking antibiotics at any one time. The problem is that in up to 50% of those cases, antibiotics were unnecessary and the condition would have improved without them. It is essential that we seek to educate people on the use of antibiotics, and that our GPs and others doing the prescribing use them far less.

Resistance is, of course, a natural biological phenomenon, but it is increased by the misuse of medicines and poor infection control. It is a particular concern with regard to antibiotics. Many of the medical advances we have made over recent years—such as organ transplantation and even chemotherapy—need antibiotics to prevent and treat the bacterial infections that such treatments can cause. Without effective antibiotics, even minor surgery and routine operations become high-risk here in the UK.

[Patrick Grady (Glasgow North) (SNP)]

I congratulate the hon. Members who secured the debate and apologise for having been unable to attend it from the start and take part more fully. I agree with a lot of the points my hon. Friend is making. Antimicrobial resistance is hugely important. I do not know whether she is aware of the antibiotic champion scheme, which encourages policy makers, decision makers and others in the professional field to sign up to promote the various steps we can take to tackle antimicrobial resistance. Those steps include completing the course of antibiotics, which is particularly important if people have taken them prophylactically when they have travelled in developing countries, to prevent malaria and so on.

[Carol Monaghan]

I thank my hon. Friend for his intervention. I am an antibiotic champion and I have signed the pledge, but we need more people to not just be aware of that pledge, but take action and follow the steps that it includes.

Inaction on antimicrobial resistance will mean the loss of effective antibiotics, which will undermine our ability to fight infectious diseases, not only in the UK but worldwide. There are many challenges in the current antibiotic funding landscape. The expected returns and associated risks mean that antimicrobials are not competitive with other therapeutic areas. Innovative new antibiotics often have a low price, because society expects antibiotics to be available easily and to be economical, but that low price means that it is not in the interests of the pharmaceutical companies to go ahead and develop new antibiotics. We need to think about that. No new category of anti-TB drug has entered the standard treatment list since 1967—in 50 years—because although TB does occur in major cities around the world, it is still a poor-country disease and there is no economic incentive to provide new treatments. We should be pushing on that from a moral point of view, though, because there is a moral incentive.

When talking about development, we should not underestimate the effects of Brexit. As a couple of hon. Members, particularly the hon. Member for Stafford (Jeremy Lefroy), have said, the EU nationals who work in research and development in the UK’s world-leading centres must have their ability to remain here guaranteed. A large percentage of the staff at the University of Glasgow’s Centre for Virus Research, which is in not my constituency but that of my hon. Friend the Member for Glasgow North (Patrick Grady), are EU nationals—postgraduate and postdoctorate researchers who are doing outstanding work in the field and advancing our knowledge and ability to treat disease.

[Patrick Grady]

I thank my hon. Friend for giving way again. I had the huge pleasure of visiting the Centre for Virus Research in my constituency just a couple of weeks ago. The staff there undertake world-leading work, so the point she is making about our need to continue to attract the best talent from the European Union is vital. She mentioned the moral case; does she agree that it is also vital that the funds, particularly those that come through the Government’s commitment to the 0.7% aid target, are still available for research? I hope that when the Minister responds, he will be able to reinforce the Government’s commitment to that 0.7% target, unlike some of his colleagues earlier today.

[Carol Monaghan]

I very much agree on the 0.7% target. That figure for aid is as important to tackling infectious diseases as guarantees for the EU nationals who are fighting infectious diseases worldwide.