Oral Answers to Questions

David Amess Excerpts
Monday 9th February 2015

(9 years, 2 months ago)

Commons Chamber
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Theresa May Portrait Mrs May
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I must tell the hon. Lady that her analysis is wrong. This Government did make a difference to the Prevent programme when they came to office. We observed that, all too often, people were seeing the Labour Government’s integration work under Prevent through the prism of the Government’s spying on them, and of counter-terrorism, so we changed the way in which Prevent operated. The Home Office has not cut its funding for Prevent, and I am pleased to say that Prevent programmes have reached more than 50,000 people in this country.

David Amess Portrait Sir David Amess (Southend West) (Con)
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8. What steps her Department is taking to tackle identity crime.

Karen Bradley Portrait The Parliamentary Under-Secretary of State for the Home Department (Karen Bradley)
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We have developed a programme of activity to tackle the important issue of the manufacture and use of false identities, working closely with the national policing lead on identity crime.

David Amess Portrait Sir David Amess
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Does my hon. Friend agree that the Specialist Printing Equipment and Materials (Offences) Bill, which is being taken through its final stages in the House of Lords by Baroness Berridge, is vital to tackling the dire situation that is being caused by identity fraud?

Karen Bradley Portrait Karen Bradley
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I pay tribute to my hon. Friend for his Bill, which the Government fully support. I know that, once it has completed its passage through the other place, it will make a significant difference to the tackling of identity crime.

Counter-Terrorism and Security Bill

David Amess Excerpts
Tuesday 9th December 2014

(9 years, 4 months ago)

Commons Chamber
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Diana Johnson Portrait Diana Johnson
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I thank the Minister for going through all the questions that I posed. On the basis of what he has said, I happily beg to ask leave to withdraw the amendment.

Amendment, by leave, withdrawn.

Clause 17 ordered to stand part of the Bill.



Clause 18

Authority-to-carry schemes

Question proposed, That the clause stand part of the Bill.

David Amess Portrait The Temporary Chair (Mr David Amess)
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With this it will be convenient to discuss the following:

Clauses 19 and 20 stand part.

That schedule 2 be the Second schedule to the Bill.

James Brokenshire Portrait James Brokenshire
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Part 4 and schedule 2 deal with aviation, maritime and rail security. For the benefit of the Committee, I will go through each of the provisions, listen to right hon. and hon. Members’ contributions and then respond to their questions. I welcome the right hon. Member for Delyn (Mr Hanson) to the Opposition Front Bench. He has taken a close interest in these issues.

Clause 18 provides a new legal basis for the operation of authority-to-carry schemes, which are commonly known as no-fly schemes. We have a scheme in place that relates to passengers being carried to the UK. The clause makes provision for a broader scheme that relates to individuals who are arriving or are expected to arrive in the UK, and individuals who are leaving or are expected to leave the UK.

Authority to carry is necessary to prevent the entry or return to the UK of foreign nationals who pose a terrorism-related threat and to mitigate the threat of an attack, primarily on aircraft. It is also necessary to disrupt the return to the UK, and prevent the departure from the UK, of British nationals who are subject to legal restrictions on their travel. Under the clause, any scheme must set out the carriers to which it applies and the classes of individuals a carrier may be refused authority to carry to or from the UK. Classes of individuals may be specified in a scheme only if it is necessary in the public interest. When travelling to the UK, that could include persons who are excluded or have been deported from the UK, individuals whose presence in the UK would not be conducive to the public good, and those who would otherwise be inadmissible to the UK. It may also include individuals subject to a temporary exclusion order under clause 2.

When travelling from the UK, carriers might be directed not to carry individuals subject to a TPIM or a post-custodial licence preventing travel following a conviction for a terrorism-related offence. The scheme may also include individuals who have had their passport cancelled or not issued on public interest grounds, or seized under powers in schedule 1. Any scheme must set out the process for carriers to request authority to carry, and state how that authority is granted or refused. That may include requirements for carriers to provide passenger information by a certain time before departure, or for carriers to be able to receive information that grants or refuses authority to carry in a way compatible with the Government’s border system.

We will work with carriers to resolve any compliance issues, but if a carrier fails to comply, clause 19 provides regulations to impose a civil penalty on those who breach a scheme. The new regulations set out how a penalty will be calculated, imposed and enforced, and must provide a means for carriers to object to a proposed penalty. The regulations are subject to the affirmative procedure, and the authority-to-carry scheme to which the regulations refer must be laid in Parliament at the same time.

Clause 20 makes provision for schedule 2 to the Bill. Part 1 of schedule 2 amends passenger, crew and service information relating to aircraft and ships, and may be extended to international trains through secondary legislation. Paragraphs 1(2) and 1(3) mean that a carrier may be required to be able to receive communications about information that it has provided to the border authorities in a way compatible with the Government’s border system. That might be a simple receipt, or an alert about errors in the format of the information.

Paragraphs 1(4) and 1(7) of schedule 2 allow the regulations to introduce requirements for advance information about persons on flights or voyages to and from the UK that do not operate to a published schedule—collectively referred to as “general aviation” and “general maritime.” The regulations will set out the classes of ships or aircraft to which they apply, the information required, the time by which it must be supplied, and how it is to be supplied. That will allow a much clearer picture of incoming and outgoing traffic and the identification of aircraft and ships that require close attention from the border authorities. Those paragraphs also provide for regulations to impose a civil penalty for a failure to comply with new requirements to provide information. The regulations may set out how a penalty will be calculated, administered and enforced, and make provision for an appeal.

Specialist Printing Equipment and Materials (Offences) Bill

David Amess Excerpts
Friday 5th December 2014

(9 years, 4 months ago)

Commons Chamber
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David Amess Portrait Mr David Amess (Southend West) (Con)
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I beg to move, That the Bill be now read the Third time.

I say immediately what a pleasure it is to see my hon. Friend the Minister on the Front Bench. It seems just a short while ago that he and his now wife used to campaign for me, in those halcyon days in Basildon. It is very good that he is the Minister responding to the debate. I also want to praise our hon. Friend the Member for Dover (Charlie Elphicke), who piloted the Bill through the House last year but did not have my good fortune. I also thank all Members for giving up their valuable time and serving in the Committee.

I am sure the House will agree that the available figures for identity crime are worrying. Figures published by the National Fraud Authority revealed that almost one third of UK adults had been the victim of identity crime at some point. It is estimated that 4.3 million adults were victims in 2012 alone. Of those, 2.7 million lost money, with an average of £1,200 lost per person. To the most vulnerable members of our society, the damage caused goes much further than just this loss of money. Some victims spend a lot of time attempting to clear their names and are chased by debt collection companies unaware that the person has been the victim of identity crime.

Of course, criminals are not concerned about the damage they cause and will continually try to stay ahead of the game by obtaining the latest specialist printers to make a wide range of false documents. They rely on members of the specialist printing industry to supply the specialist printing equipment to them, either by tricking suppliers into thinking they will use it for legitimate purposes, or by colluding with unscrupulous specialist printing companies. By supplying this equipment to people who will use it to commit crime, they enable some of the most serious crimes affecting this country and compromise the safety of the public.

I recently met the Metropolitan police, and was concerned to hear that they have numerous recent examples of illegal document factories being uncovered and documents relating to thousands of identities being found. This includes passports, driving licences, birth certificates, immigration documents, EU identity cards, national insurance number cards—the list goes on. However, in none of these cases has the police been able to prosecute those who supplied the specialist equipment to the criminals, even when there was evidence that they knew what the equipment would be used for. That is why the Bill is needed.

David Nuttall Portrait Mr David Nuttall (Bury North) (Con)
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I congratulate my hon. Friend on getting his Bill through to Third Reading. I was delighted to serve on the Bill Committee. Will he confirm for the benefit of the House that the Bill will place no costs on business—no extra regulation or bureaucracy—and that the only people who will suffer as a result of the Bill are the criminals, who deserve to suffer?

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David Amess Portrait Mr Amess
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My hon. Friend, whom I thank for serving on the Committee, makes an excellent point: there will be no cost to the public purse, other than the cost of the courts and prosecutions.

The Bill will support the police in targeting rogue suppliers who collude with criminals, and if there is evidence that an individual or business has knowingly supplied specialist printing equipment for criminal purposes, they could face imprisonment for up to 10 years and/or an unlimited fine. It covers the manufacture of documents that can be used for a range of identity purposes of the type I have outlined. These documents provide the holder with access to various services and benefits across both the public and private sectors.

In the wrong hands, false versions of these documents can cause untold damage, including enabling illegal immigrants to merge into our society and fraudulently access public services to which they are not entitled. Crime committed through the use of false documents can have a serious impact on businesses, particularly small businesses, and that can also have a serious impact on the economy. The Bill provides a simple and targeted measure to deal with this serious problem. We recognise that false document factories are a cross-border problem, so this Bill will apply to the supply of specialist printing equipment for criminal activity occurring in any jurisdiction. If a supplier in England and Wales sells equipment to an identity fraudster knowing that they will use it to manufacture false documents, they will themselves be prosecuted, whether the manufacture itself happens in England, Scotland, France or even Australia.

This Bill will empower the police to deal effectively with those who seek to profit from identity crime. It sends a clear message that if anyone knowingly supplies specialist printing equipment to criminals, they will face the consequences and be prosecuted.

Oral Answers to Questions

David Amess Excerpts
Monday 2nd December 2013

(10 years, 4 months ago)

Commons Chamber
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Robin Walker Portrait Mr Robin Walker (Worcester) (Con)
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2. What steps she is taking to tackle the supply of illegal drugs.

David Amess Portrait Mr David Amess (Southend West) (Con)
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8. What steps she is taking to tackle the supply of illegal drugs.

Norman Baker Portrait The Minister for Crime Prevention (Norman Baker)
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We are committed to tackling the supply of illegal drugs in the UK and overseas. Action to restrict drug supply is a priority for the police and the new National Crime Agency. The coalition Government’s new serious and organised crime strategy emphasises the importance of tackling the organised crime that is associated with the drugs trade.

Norman Baker Portrait Norman Baker
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Yes, I do agree with that. I am pleased to hear that robust action is being taken to damage that trade in my hon. Friend’s area and elsewhere in the country. I agree that visible law enforcement activity can be effective in restricting the supply of drugs and I am pleased to see the partnership in West Mercia and Warwickshire to steer drug misusers into treatment.

David Amess Portrait Mr Amess
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Will the Minister join me in congratulating the Border Force and the National Crime Agency on their recent seizure of 850 kg of cocaine and does he agree that that shows that our approach to securing borders and tackling organised crime is paying dividends?

Norman Baker Portrait Norman Baker
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I congratulate the National Crime Agency and Border Force on that seizure, which is believed to be the largest cocaine seizure in Britain for more than two years. It is a good example of the benefits that intelligence sharing and partnerships between law enforcement agencies can bring about in disrupting drug traffickers and other criminals. That is a key element in our efforts to tackle organised and serious crime.

Oral Answers to Questions

David Amess Excerpts
Thursday 14th February 2013

(11 years, 2 months ago)

Commons Chamber
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Lord Vaizey of Didcot Portrait Mr Vaizey
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I have already met a number of MPs to discuss the issue and I would be delighted to meet the hon. Lady and any hon. Members she wishes to bring with her. I share her concerns. This is important and there are two regulators—Ofcom and the Information Commissioner’s Office—and I meet them regularly to discuss this issue. I would happily bring them to the meeting.

David Amess Portrait Mr David Amess (Southend West) (Con)
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16. When she expects a decision to be made on which city will be named 2017 UK city of culture.

Lord Vaizey of Didcot Portrait The Parliamentary Under-Secretary of State for Culture, Media and Sport (Mr Edward Vaizey)
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We expect to announce the result of the competition for UK city of culture 2017 in November.

David Amess Portrait Mr Amess
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Although I fully appreciate that my hon. Friend must go through the formalities of the bidding process as to which city should be city of culture in 2017, he could save his time and the work of his officials by announcing now that Southend should be the city of culture.

Lord Vaizey of Didcot Portrait Mr Vaizey
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The cultural delights of Southend are well known: the Pier Cultural Centre, Priory Park bandstand and, of course, the Cliffs Pavilion where tonight Billy Fury’s Tornados will be playing. No doubt they will perform “Last night was made for love”.

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Lord Vaizey of Didcot Portrait Mr Vaizey
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I would be absolutely delighted, and I have indeed visited the theatre in Plymouth in the past.

David Amess Portrait Mr David Amess (Southend West) (Con)
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T6. Will my right hon. Friend visit the Jubilee Room on 4 March, where she will see at first hand just how wonderful Southend is? She will learn that the only way is Essex in terms of culture, media and sport.

Maria Miller Portrait Maria Miller
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My hon. Friend is a very persuasive Member of Parliament, and I am sure that as many MPs as possible will be there.

Oral Answers to Questions

David Amess Excerpts
Monday 11th February 2013

(11 years, 2 months ago)

Commons Chamber
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James Brokenshire Portrait James Brokenshire
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I do not accept the right hon. Gentleman’s point. Indeed, in evidence to the Home Affairs Committee, the Metropolitan Police Commissioner did not say that a parallel such as that the right hon. Gentleman seeks to make could be drawn. We are reviewing the incident closely, as we would any incident of this kind, and if practical issues need to be adopted we will certainly consider and adopt them.

David Amess Portrait Mr David Amess (Southend West) (Con)
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18. what steps she has taken to tackle human trafficking groups in their country of origin.

Mark Harper Portrait The Minister for Immigration (Mr Mark Harper)
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The UK works closely with partners in source countries to disrupt organised human trafficking gangs. We work hard to apprehend criminals both in those countries and in the United Kingdom.

David Amess Portrait Mr Amess
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What assessment has my hon. Friend made of section 14 of the Policing and Crime Act 2009 in protecting the victims of trafficking in the UK domestic prostitution market?

Mark Harper Portrait Mr Harper
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That issue was raised during a recent debate in Westminster Hall, and the Government continue to keep it under review. My hon. Friend may be interested to know that this afternoon I will meet officers of the all-party group on human trafficking, including my hon. Friend the Member for Wellingborough (Mr Bone), the Baroness Butler-Sloss and Anthony Steen, and I hope we will have further discussions in due course.

Oral Answers to Questions

David Amess Excerpts
Monday 12th December 2011

(12 years, 4 months ago)

Commons Chamber
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John Bercow Portrait Mr Speaker
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The hon. Gentleman is in danger of setting a trend. If others followed it, our proceedings would conclude more speedily. I am grateful to him for his self-denial.

David Amess Portrait Mr David Amess (Southend West) (Con)
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T1. If she will make a statement on her departmental responsibilities.

Theresa May Portrait The Secretary of State for the Home Department (Mrs Theresa May)
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As the House just heard, this Government are committed to controlling immigration and reducing net migration. We have already introduced an annual limit on the number of non-EU workers, overhauled the student visa route and increased enforcement activity. Our next steps are to break the link between temporary and permanent migration by restricting settlement rights and to reform family migration. Members of this House have played a crucial role in shaping these reforms and I welcome the opportunity for further such contributions in this afternoon’s Government debate, which will be ably led by my hon. Friend the Minister for Immigration.

David Amess Portrait Mr Amess
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While I recognise that my right hon. Friend has a very tough job as Home Secretary, does she understand my disappointment? When I first became MP for Basildon, we had one police station; by the time I left we had three and Lord Mackay of Clashfern had opened a magnificent courthouse. I then became the Member of Parliament for Southend West, where there are a huge number of elderly people and where I started off with three police stations, and I will shortly have none.

Animal Experimentation

David Amess Excerpts
Wednesday 7th December 2011

(12 years, 4 months ago)

Commons Chamber
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David Amess Portrait Mr David Amess (Southend West) (Con)
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Throughout my time in Parliament I have consistently campaigned on animal welfare issues. I do not believe that I have been unreasonable, extreme or silly about those issues, but I have endeavoured to ensure that animals’ interests have been represented in this Chamber. By virtue of a ten-minute rule Bill, together with Lord Houghton of Sowerby and the then Minister, Douglas Hogg, I was fortunate to secure on the statue book the Protection against Cruel Tethering Act 1988. There are many other animal welfare measures regarding pet shops, exotic and endangered species, puppy farming and the like which I have tried to encourage through legislation. In 1986 I served on the Committee that considered the Animals (Scientific Procedures) Bill.

In 1876 Parliament passed the first legislation in any country in the world to control live experiments that might cause pain. The Cruelty to Animals Act 1876 was a response to some horrifying reports about the practice of surgical procedures on live animals without anaesthesia. That Act stood the test of time well, but the 1986 legislation brought it up to date. I well remember the then Minister, David Mellor, doing battle with the former Member of Parliament Harry Cohen. It was a very interesting exchange of views, but I am glad that the measure that ultimately reached the statute book was well appreciated.

The European Union has adopted a new directive on animal testing—Directive 2010/63. I point out to the Minister that the Home Office will be amending the Animals (Scientific Procedures) Act 1986 to comply with the directive. A number of colleagues have already contacted me to say that they are very concerned about this matter. It is true that there will be a public consultation, and I understand that the Home Office is currently analysing responses and putting together a draft proposal that will be sent to Parliament next year. However, my colleagues and I are very concerned about the European directive, simply because we in this country pride ourselves on the way in which we treat animals, and we need to be convinced that all countries in the European Union have the same high standards as we do.

Our country is allegedly a nation of animal lovers. Sadly, words and actions do not always match up. I consider the measure of a civilisation to be how animals are treated. I pay tribute to the many organisations and groups that battle to stop cruelty to animals, helping to generate support and awareness about various issues. As regards the particular matter that I wish to raise with the Minister, I am indebted to Kathy Archibald and Louise Owen, who, among others, have briefed me so well. Indeed, they are probably on the line now, hoping that I can make changes to the speech and get in yet another piece of lobbying.

Writing in Nature Reviews Drug Discovery, David Horrobin answered the question:

“Does the use of animal models of disease take us any closer to understanding human disease?”

His response echoes the concerns that I wish to raise in the House tonight:

“With rare exceptions, the answer to this is likely to be negative.”

The process before clinical drugs come to be tested on a human being should be well understood, but I am not sure that it is. Anyone who hopes to get a new drug on to the market must first put it through a series of tests on various animals. It is that reliance on animals as a final safety screen before products go to clinical trials that concerns me, for that “safety screen” is no such thing. Animal models are not a reliable indicator of how a human being will react to a drug.

My hon. Friend the Member for Stourbridge (Margot James), who has just taken her place, will be glad to hear that I have already raised the European directive that she is concerned about, and that the Minister nodded. I am therefore optimistic that Home Office officials will be working on the advice right now.

The safety of medicines is an issue of increasing concern. Every year, 1 million Britons are hospitalised by prescription medicines. That costs the NHS up to £2 billion a year. The Safety of Medicines Bill, which I introduced earlier this year, is intended to safeguard against this growing problem. I believe that the Bill has widespread support—but then I would say that. However, it has been misrepresented, although not intentionally I am sure, and it has certainly been misunderstood. Although my opposition to cruelty to animals is well documented, it is important to make it absolutely clear that the Bill does not call for animal tests to be replaced per se. It is about determining the best means to ensure the safety of medicines and to protect patients against adverse drug reactions.

It could be argued that the use of animals is ethically and morally wrong. Many people would argue that strongly. However, in this debate the criticism of the use of animals focuses not on the suffering of the animal, which can be quite shocking, but on the fact that animal models are not accurate indicators of human responses. That in turn creates risks for volunteers, patients and sufferers during and after human clinical trials. I believe that there is ample evidence to support the argument that animal models do not function properly in their role.

Jim Shannon Portrait Jim Shannon (Strangford) (DUP)
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I do not often disagree with the hon. Gentleman or question him. However, there are many examples of medicines that have been perfected by their use on animals and have saved lives. How will he ensure that that continues to happen, given what he has been setting out? My concern is that there is some goodness in this practice. Let us not lose that.

David Amess Portrait Mr Amess
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The hon. Gentleman and I do not disagree on many things, and it would be a shame if we fell out on this issue. I hope to prove by the end of my contribution that there would certainly not be the adverse impact that he fears.

Chris Williamson Portrait Chris Williamson (Derby North) (Lab)
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I congratulate the hon. Gentleman on bringing this issue before the House, and I very much support him. I am sure that he is going to come on to this point, but my response to the hon. Member for Strangford (Jim Shannon) would be that in an infamous case, thalidomide was proven safe for use on animals, but we all saw the tragic consequences of that. There has been a lot of publicity about that, but there are many other examples that have not had the same level of publicity. As the hon. Member for Southend West (Mr Amess) pointed out—before the hon. Member for Strangford came into the Chamber, I think—1 million people a year are hospitalised as a result of taking prescription medication. We must consider that problem, and I hope that the Minister will listen to the contribution of the hon. Member for Southend West this evening.

David Amess Portrait Mr Amess
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I welcome the support of the hon. Gentleman, whose maiden speech I was privileged to follow. I am going to mention two or three cases that enforce what he says.

There is ample evidence to support the fact that animal models do not function in their role. That is a very important matter for the Home Office to consider. In my time here many Ministers have held the relevant responsibility, and of course those advising Ministers are also very important. I do not expect the Minister to give me a firm yea or nay during the debate, but I hope she will write to me about the points that I make.

Experiments on animals cannot predict the mechanisms of the disease in question, risk factors or potential adverse reactions. According to the US Food and Drug Administration, the world’s largest drug regulator—I hate to keep using America as the example, but it seems to have the latest data—92% of potential new drugs fail in human trials. We cannot just dismiss that, because it is huge number, but no publicity is given to it. The drugs fail either because they do not work on, or are not safe for, humans. I will come later to one famous and disastrous incident. After appearing safe and effective in animal tests, those drugs fail completely.

Communities of senior scientists are very much aware of the dangers of using animals as human indicators. The Safer Medicines Trust, the patient safety charity of senior scientists, including Sir Ian Wilmut, the renowned “father” of Dolly the sheep, has expressed its concern. It is clearly not opposed to animal experimentation per se, but it is concerned for patients and for science in general. Indeed, it has sent open letters to the Prime Minister and the Secretary of State for Health stating that the current system for ensuring the safety of medicines before clinical trials is inadequate and results in harm to volunteers and patients.

These are difficult times, and I know that people are paid to volunteer for trials, but there have been a number of well-documented disastrous consequences. The danger to human beings from the use of animal testing is clear. Even in pre-clinical stages, lives have been lost because the results have misled scientists.

I wonder how many people realise that penicillin stayed on the shelf for more than a decade because the results in the rabbits on which Fleming tested it led him to believe that it would be ineffective in humans. That was quite the wrong outcome—and we can think of the number of lives that could have been saved all those years ago.

Lives are threatened in the human clinical stages of trials. In March 2006 six young men took part in a clinical trial at Northwick Park hospital and were nearly killed by a drug that had been tested on monkeys and shown to be safe, even at 500 times the dose that the men were given. That is not a trivial matter, and I can remember clearly when it happened. Again, I do not expect the Minister to respond now, but I hope that after she has taken advice she will be able to discuss what happened in that trial.

Clearly, the results from the monkeys created a false sense of security, yet the risk carries over even when drugs pass to market. Any number of hon. Members will have had constituents lobby them on the painkiller Vioxx, which was eventually withdrawn in 2004 after the biggest drug disaster in history—it killed more than 100,000 people worldwide in its five years on the market. Clinical trials of Vioxx revealed up to a fivefold increase in the risk of a serious reaction such as heart attack, heart failure or stroke, but tests on animals indicated that it was safe, and in some instances that it was protective to the heart, which supported the manufacturer’s decision to market the drug. I am currently dealing with two or three constituents whose loved ones were affected by the drug, and who are trying to get compensation, which, as hon. Members know, is quite a tough battle. One hundred thousand people were affected worldwide.

Why should animals be indicators of human response? Animals and humans are evolved complex systems and as such should be expected to demonstrate different responses to drugs and disease.

Margot James Portrait Margot James (Stourbridge) (Con)
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A number of drugs registered for humans are effective in animals. Dogs in older age respond very well to Prozac if they are a bit down, and a hypertension drug for humans has proved effective in restoring the vitality of apes in zoos in Britain.

David Amess Portrait Mr Amess
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I apologise to my hon. Friend in case I was going too far on one side; my argument needs to be balanced.

Mutations that cause genetic disease in humans are the norm in some animals. Johnson et al found in 2001 that out of 39 anti-cancer drugs tested on xenograft mice, only one mimicked the response in humans. I say to the hon. Member for Strangford (Jim Shannon) that that cannot be much to rely on.

Jim Shannon Portrait Jim Shannon
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We need balance in the debate because we are getting one side of the argument but not the other, which is that drugs have been successful in saving lives. I am not taking away for one second from those who have died as a result of inappropriate drugs but, with respect, we need that balance, but we are not getting it.

David Amess Portrait Mr Amess
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Frankly, one life lost is too many, but we could have a big argument—

Jim Shannon Portrait Jim Shannon
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One life saved is worth it.

David Amess Portrait Mr Amess
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Yes, I agree with the hon. Gentleman that it is a question of balance, but I hope to prove that animal experimentation is completely unnecessary and that we can achieve the same results through different methods.

There is a variation of response within humans—African Americans are more susceptible to lung cancer than Caucasians—so how can we expect animals to be reliable models?

Using animals as human indicators is also expensive, for it can keep cures off the market, hence the large cost of modern drugs to consumers and the health service generally. In the words of Robert Weinberg, from the Massachusetts Institute of Technology, the use of pre-clinical tests results in

“hundreds of millions of dollars…being wasted every year by drug companies using these [animal] models”,

according to Leaf 2004.

Other areas of valuable research that might help in understanding the impact of drugs in human beings suffer as a result of animal testing. Despite animal models forming a very minor part of research, they receive a large proportion of funding. Society does not need new research methods; it simply needs to fund the ones that we already have. The important point is that it is possible to test these clinical drugs on humans, so that we can have a better indication of how they will react pre and post-clinical trials.

Society needs to make a fundamental change from animal-based research to human-based research. If it is humans whom we are trying to help, then scientists must study disease and drug reactions in humans. New technologies, outlined by the Safer Medicines Trust, are based on monitoring human responses to new drugs in a variety of ways. Those range from combinations of tissues in “body-on-a-chip” devices to safe volunteer studies such as micro-dosing, where tiny amounts of a new drug are administered to human volunteers. Scientists, in turn, evaluate what the drug does to the body and what the body does to the drug. Micro-dosing in particular has shown to be highly predictive of results in the clinic. Astoundingly, these tests are already commercially available from a number of UK companies, and offer a much safer and less risky alternative to using animals in clinical trials.

More than 150 colleagues have signed a motion calling on the Government—it is Christmas and this is not too much to ask—to initiate a small, cheap comparative study to demonstrate whether these new technologies are indeed superior. Sadly, the Government are resisting such a study and insist that human biology-based tests are not better able to predict adverse drug reactions than animal tests, despite scientific evidence to the contrary.

Roger Williams Portrait Roger Williams (Brecon and Radnorshire) (LD)
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The hon. Gentleman makes a compelling argument. Indeed, no one doubts his sincerity. However, if these human-based tests were more effective and cheaper than the animal tests, why are the commercially sensitive companies not taking that route? Why do they persist with animal testing?

David Amess Portrait Mr Amess
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I am not going to fall out with a tough farmer, because the hon. Gentleman and I have perhaps slightly different views about animals generally. I understand his point, but he will be pleasantly surprised to find that there are many companies that now want to go for this different option. I have taken a lot of advice on it and we just need a little more encouragement from the Home Office and its advisers.

The attitude at the moment—I do not wish to be unkind to the Home Office—typifies the herd mentality that we are facing; a mentality that aims to promote quantity of opinion and that goes against the pioneering mentality of many breakthrough scientists. The comparison with human biology-based methods has attracted high-level support among scientists. Some 83% of GPs who were surveyed were in favour. Many colleagues have supported the early-day motion and I have received strong support for the Safety of Medicines Bill. All the scientists at the conferences of the Safer Medicines Trust in the House of Lords and the Royal Society were also in favour of my Bill.

The British Union for the Abolition of Vivisection is concerned that Britain is not one of the countries, such as Austria and Belgium, that has urged the European Commission to stand firm on an animal ban for cosmetics without exceptions, as was provisionally agreed by the European Union for 2013. That is not acceptable. Although I welcome the Government’s commitment to trying to encourage a reduction in animal experiments, there has so far been a lack of new initiatives to reverse what the evidence shows is a rising trend. I know that the Minister has received more than 20 proposals from the BUAV for policy changes. I very much hope that she will respond to those 20 points in correspondence.

Let me conclude with these thoughts. I am talking about negligible expenditure on a comparative study. The amount is quite small relatively, and—I say this to the hon. Member for Brecon and Radnorshire (Roger Williams)—pharmaceutical companies will willingly fund such a study, which would therefore not impose a cost on the public purse. Such a study could save the billions of pounds that are currently wasted on animal testing by reducing ADRs and boosting pharmaceutical company efficiency. Critically, the sheer scale of ADRs and the fact that they are increasing at twice the rate of prescriptions means that we have an ethical imperative to take action to address what is a serious public health problem, with reported deaths up by 155%, according to The Independent. The key question is this, and I hope that the Minister can answer it—if she cannot, I would appreciate it if she wrote to me: on what basis do the Government refute the evidence that a number of human biology-based tests have predicted ADRs that animal tests failed to predict?

As we move towards Christmas celebrations, we are drawn to the image of the nativity, with the infant baby Jesus and his parents surrounded by animals. The image and the link could not be clearer. I trust that the Government will reflect on what I have said today and ensure that the proposals in the Safety of Medicines Bill, which I introduced earlier this year through the ten-minute rule procedure, can be enshrined in legislation, as the final gift, after gold, frankincense and myrrh, to both kingdoms represented by the nativity.

DNA and CCTV (Crime Prevention)

David Amess Excerpts
Tuesday 6th July 2010

(13 years, 9 months ago)

Westminster Hall
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rose

David Amess Portrait Mr David Amess (in the Chair)
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Order. Winding-up speeches begin at 12.10 pm. Three hon. Members wish to speak. I believe that it will be a minute and a bit for each of them. I call Andrew Percy.