Puberty Suppressants Trial

Debate between Wes Streeting and Carla Denyer
Wednesday 17th December 2025

(4 days, 19 hours ago)

Commons Chamber
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Wes Streeting Portrait Wes Streeting
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My hon. Friend is absolutely right. Regardless of whether people are receiving this medication or not, we need to ensure that they receive the right therapeutic support to enable them to have healthy, happy childhoods and to understand themselves, the world they live in and how they relate to it in a way that does not cause them distress or harm. That is my objective in this process.

Carla Denyer Portrait Carla Denyer (Bristol Central) (Green)
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For young people questioning their gender, the pathways trial is currently the only route by which they are allowed to access puberty blockers, which are a treatment that can provide vital respite from the anguish of going through puberty in a body that does not match your gender, before long-term decisions may or may not be made as an adult. I therefore welcome the announcement of the trial, while recognising that significant barriers to entry remain. How will the Secretary of State ensure that as many young people as need to can access the trial, including those who need to access puberty blockers as part of support to improve their mental health?

Wes Streeting Portrait Wes Streeting
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I do not doubt the hon. Member’s sincerity and integrity on this issue, but I say to her respectfully that when she talks about barriers to entry, those “barriers” are safety and clinical oversight, as well as parental consent and the assent of the young person. I do not believe that those are barriers; I believe that those are necessary bars for participation in this trial.

Puberty-suppressing Hormones

Debate between Wes Streeting and Carla Denyer
Wednesday 11th December 2024

(1 year ago)

Commons Chamber
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Wes Streeting Portrait Wes Streeting
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The details of the trial are still being worked through. They will be and are subject to a robust ethical approvals process. Only once final ethical approval is granted is the final study design set in stone. As such, I cannot comment on the finer details at this time, but I just reassure the hon. and learned Member that the issues he raises are very much under consideration in the design of the trial.

Carla Denyer Portrait Carla Denyer (Bristol Central) (Green)
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I share the concerns expressed by experts at the Council of Europe that removing access to puberty blockers except through clinical trials may breach the fundamental ethical principles governing research, amounting to coercion and therefore a breach of young people’s human rights. Exactly how harmful that decision is, however, hinges on how easy or hard it is to get on the clinical trial. How many places will there be on the trial? If he cannot at this stage, can he please reassure me that he will take careful consideration of the fact that if the trial is limited in size, that will cause harm to more trans and gender-questioning young people.

Wes Streeting Portrait Wes Streeting
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The trial will be uncapped, and I reassure the hon. Member and the House that all NIHR-commissioned research must go through robust scientific and ethical approval processes, both of which can influence final study design. In terms of the design of this trial, ethics is an integral part of the trial’s approval.