Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, how many NICE appraisals were terminated in the five-year period from 2019 to 2024, and how this compares with the preceding five-year period.

The following table shows the number of National Institute for Health and Care Excellence (NICE) appraisals that were terminated between 2019 and 2024, and between 2014 and 2019:

Source: NICE.

NICE data shows that terminated appraisals increased in 2019/20 and stabilised with no increasing trend thereafter. This followed NICE’s 2019 commitment to review all new active substances and significant indications. This required industry to submit topics which might otherwise not have been in NICE's work programme. NICE’s data shows that the proportion of terminations has been stable over the last five years, and that terminations reflect that not all products/indications will likely be clinically and cost effective. NICE will continue to monitor terminations with a view to best continuing to support access to clinically and cost-effective medicines for patients in England.