Question to the Home Office:

To ask the Secretary of State for the Home Department, with reference to data table 7.2 of her Department's statistics entitled Annual statistics of scientific procedures on living animals, Great Britain 2023: data tables, published on 11 September 2024, what legislation on medicinal products for human use required the use of dogs in regulatory procedures.

We are working with regulators to see how advances in technology can and will reduce use and phase out use in some areas.

The explicit requirement for using animals in toxicology tests comes from section 50 (5) to the Human Medicines Regulations 2012 (as amended 2019 and 2020). Therefore, in most cases, new drugs are required to be tested in two animal species for public safety and efficacy purposes. There are rare exceptions where the medicine has no pharmacological effect in any species other than humans where this may not be applied.

Although much research can be done without using animals, there are still purposes where use of live animals is essential, as the complexity of whole biological systems cannot be reliably replicated using validated alternative methodologies. Animal testing is therefore required by all global medicines regulators, including the UK’s Medicine and Healthcare Products Regulatory Agency (MHRA). We are working with regulators to see how advances in technology can and will reduce use and phase out use in some areas.