Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what assessment his Department has made of the efficacy of the Pfizer/BioNTech covid-19 vaccine when there is a 12-week gap between the first and second dose.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what assessment his Department has made of the efficacy of the Pfizer/BioNTech covid-19 vaccine when there is a six-week gap between the first and second dose.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what assessment his Department has made of the efficacy of the Pfizer/BioNTech covid-19 vaccine when there is a three-week gap between the first and second dose.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, if he will publish the data that indicates that two doses of the Pfizer-BioNTech covid-19 vaccine are still effective when administered 12 weeks apart.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what assessment his Department has made of the validity of the British Medical Association’s reported concerns on the 12-week wait for the second dose of the Pfizer-BioNTech covid-19 vaccine.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what the scientific basis was to inform the decision that one dose of the Pfizer/BioNTech COVID-19 vaccine produces enough neutralising antibodies to protect against the covid-19 virus and reduce transmission.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, if he will publish all evidence, minutes and documents relating to the decision not to implement Pfizer's recommendation that the two doses of the Pfizer/BioNTech covid-19 vaccine be administered within three weeks.
Answered by Nadhim Zahawi
A phase three clinical trial study on the Pfizer-BioNTech COVID-19 vaccine efficacy demonstrated a two-dose vaccine efficacy of 95% with a second dose delivered between 19 and 42 days.
Using data available from this study, Public Health England estimated that short term vaccine efficacy from the first dose of the Pfizer-BioNTech vaccine to be approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes the seven days after the second dose and is prior to the time protection may be expected from the second dose.
There is no estimate of efficacy for a single dose beyond 21 days. Given the data available, evidence on the AstraZeneca COVID-19 vaccine and from the use of many other non-COVID-19 vaccines, the Joint Committee on Vaccination and Immunisation (JCVI) advises a maximum interval between the first and second doses of 12 weeks. The use of ‘short-term’ in this report refers to the impact of the programme over the first months of the programme. Further information on the estimates of efficacy of one dose is available in the JCVI’s statement on 31 December which is available at the following link:
The British Medical Association have questioned the decision to use an extended schedule for COVID-19 vaccines. Data on the AstraZeneca vaccine indicate better immune responses from the second dose with an extended schedule and that protection is maintained over a twelve-week period.
The JCVI is of the view that the first dose of the Pfizer-BioNTech vaccine is likely to provide protection for at least 12 weeks.
There is no evidence to indicate a correlation between the presence of neutralising antibodies and a vaccine effect on transmission.
The JCVI aims to publish background documents to its meetings. However many of these relating to vaccine efficacy were provided to the committee in confidence or under a non-disclosure agreement and cannot be published by the JCVI. Evidence on vaccine immunogenicity and efficacy will be published by the relevant industry groups, usually in peer reviewed journals.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, how many GP surgeries have not yet received supplies of a covid-19 vaccine in (a) Leicester East constituency and (b) England.
Answered by Nadhim Zahawi
Individual general practitioner practices do not receive supplies of the COVID-19 vaccine. General practices are delivering COVID-19 vaccinations at scale, coming together in Primary Care Network (PCN) groupings to deliver the vaccine as local vaccination services. Over 1,000 PCN-led local vaccination sites are now open and offering the vaccine across England.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, what estimate his Department has made of the number of cancer patients who have had their cancer (a) diagnosis and (b) treatment delayed since the start of the covid-19 outbreak in Leicester East constituency.
Answered by Jo Churchill - Minister of State (Department for Work and Pensions)
Information is not available in the format requested for the Leicester East constituency. Monthly data on cancer activity and waiting times is collected at provider and regional level.
Asked by: Claudia Webbe (Independent - Leicester East)
Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, whether his Department has made an estimate of the number of cancer patients who are likely to have their cancer (a) diagnosis and (b) treatment delayed as a result of the latest wave of covid-19 and the January 2021 lockdown restrictions in Leicester East constituency.
Answered by Jo Churchill - Minister of State (Department for Work and Pensions)
Information is not available in the format requested for the Leicester East constituency. Monthly data on cancer activity and waiting times is collected at provider and regional level.