Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, what assessment he has made of the potential impact of NICE's draft guidance on brexucabtagene autoleucel on (a) the Life Sciences Strategy and (b) outcomes for patients with rare cancers.

The Government remains committed to the ambitions set out in the Life Sciences Sector Plan, which set out an ambition that by 2030, we will be one of the top three fastest places in Europe for patient access to medicines. We will achieve this by reducing friction in the system to optimise access and uptake of new medicines so the most clinically and cost-effective can reach patients faster.

The National Institute for Health and Care Excellence (NICE) is currently re-evaluating brexucabtagene autoleucel to determine whether it should be recommended for routine National Health Service use following a period of managed access through the Cancer Drugs Fund. NICE’s draft guidance, published in December 2025, does not recommend it as a clinically and cost-effective use of NHS resource, although NICE has not yet published final guidance. The Government recognises that the potential withdrawal of brexucabtagene autoleucel as a treatment for future patients will be concerning for patients and their families, but it is right that these decisions are taken independently and on the basis of the available evidence. In line with an arrangement between NHS England and the company, if NICE’s final guidance does not recommend use, patients who started treatment during the managed access period can continue their treatment.