Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, when details of the trial on GnRH analogue puberty blockers will be submitted to the research ethics committee.

The PATHWAYS study proposal, including the clinical trial of puberty-suppressing hormones, is going through all the usual review and approval stages. These include independent academic peer review and National Institute for Health and Care Research funding committee consideration, and it will need to secure full ethical approval ahead of set up and opening to recruitment. The researchers will submit study documents to the Health Research Authority, which will allocate a Research Ethics Committee to consider the application. As an independent study, it is for the research team to decide when the study documents are ready and they will choose when to submit the application, bearing in mind the trial is aiming to begin recruiting participants later in spring 2025.