1 Caroline Nokes debates involving the Department for Science, Innovation & Technology

Mon 19th Feb 2024

Animal Testing

Caroline Nokes Excerpts
Monday 19th February 2024

(2 months, 2 weeks ago)

Westminster Hall
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Elliot Colburn Portrait Elliot Colburn
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I am grateful to my hon. Friend for that intervention; I think that more than 100 of her constituents signed this petition too. I hope that the Minister heard her request—indeed, I am sure that it is an ask of all of us in the Chamber today. What is being done, and what more can be done, to try to encourage people out of using animals and into using non-animal methods?

I want to pick up again the point about animal welfare. Many people will cite the regulations that are in place in the UK for animals in experiment environments. However, this statistic might shed some light on why welfare standards are so low. As of 2021, there were only an estimated 23 full-time equivalent inspectors in the United Kingdom. That is 23 inspectors trying to look at 3 million different procedures. The fact that so much self-reporting is going on in the industry and there are so few inspectors leads, again, to the argument that non-animal methods are a much better use of money and bring with them higher ethical and moral standards.

I want to go through some of the proposed solutions before I hand over to some of my colleagues. PETA—People for the Ethical Treatment of Animals—has proposed a solution known as the research modernisation deal, or RMD, which offers a strategy to eliminate the use of animals in biomedical research, regulatory testing and education. It prioritises non-animal methods, conducts critical reviews to assess the necessity of animal use, and reallocates funds to non-animal methods. This is aimed specifically at making the UK once again a leader in innovative, ethical scientific practices. Furthermore, we have seen advances in technology such as in vitro and in silico tests, and innovative technologies such as organs on chips, which offer higher levels of protection and prediction accuracy.

Elliot Colburn Portrait Elliot Colburn
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That is one of the things I want to stress, but before I do so, I will give way to the Chair of the Women and Equalities Committee.

Caroline Nokes Portrait Caroline Nokes
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My hon. Friend makes the really important point that non-animal methods can be much more accurate than using animals in these experiments. Does he agree that companies such as Lush, which came to Parliament before Christmas to advocate for those methods, have shown the way in which, through science, we can do better?

Elliot Colburn Portrait Elliot Colburn
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I absolutely agree with my right hon. Friend. This is something that we cannot stress enough in this debate: it has been proven in the data time and again that non-animal methods are highly accurate, and much more accurate when it comes to predicting human responses than animal testing is. In fact, animal testing has such low levels of success when it comes to measuring how a drug or something else might affect a human that we would not accept that in any other form of business. When the levels of prediction are so poor, why are we still accepting it? It does not make any sense—not when we have alternatives that can offer much greater clarity about to how humans will react to products and drugs.

However, there are challenges standing in the way, and one of them remains funding for NAMs. Pfizer and AstraZeneca have said that they do not want to do things such as secondary species testing, but regulatory guidelines often expect new drugs to be tested on animals and there is a lack of consensus on possible transition timelines. There is also push-back from the industry, which is resistant to change. However, in advance of this debate I spoke to many scientists and industry leads who said they are crying out for change and want to be at the forefront of non-animal methods. We need to give them the tools to do so and look at the way we fund research.